Celastrol CAS 34157-83-0

CAS:34157-83-0

Tātai ngota:C29H38O4

Taumaha ngota:450.61

EINECS:636-472-5

Ngā kupu taurite:CELASTROL(SH); CELASTROL; Celastrol (Tripterin); CELASTROL(P)(TĒNĀ WAEA MAI); (20R)-3-Hydroxy-2-oxo-24-nor-D:A-friedoolean-1(10),3,5,7-tetren-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedela-1(10),3,5,7-tetraene-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic acidCelasterol

Waiho tō karere

Taipitopito Hua

Tikiake

Ngā Tohu Hua

He aha te Celastrol CAS 34157-83-0?

Kāore a Celastrol e wairewa i roto i te wai, engari e wairewa ana i roto i te dimethyl sulfoxide me te anhydrous ethanol. I ahu mai i ngā matū hohe ārai-matepukupuku i roto i ngā tipu pērā i a Thunder God Vine me South Snake Vine i roto i te whānau Celastraceae. He aukati proteasome whai hua, kua whakaūtia ka whakaoho i te apoptosis pūtau matepukupuku mā te aukati i te mahi proteasome.

Whakatakotoranga

Taonga	Whakatakotoranga
Te pūwāhi koropupū	645.7±55.0 °C (I matapaetia)
Kiato	1.2
Te pūwāhi rewa	219-230°C
pKa	4.78±0.70 (I matapaetia)
λmaximum	424nm(MeOH)(whakamārama)
Ngā tikanga rokiroki	-20°C

Tono

Ka whakamahia a Celastrol mō te whakatau/te tautuhi i ngā ihirangi/ngā whakamātautau rongoā, me ētahi atu. Ngā pānga rongoā: He kaha ōna āhuatanga ārai-matepukupuku, he pānga ārai-matepukupuku, me ngā pānga ārai-matepukupuku. He aukati proteasome whai hua, kua whakaūtia ka whakaoho i te apoptosis pūtau matepukupuku mā te aukati i te mahi proteasome.